To create responsive designs in Tailwind CSS, you can use the utility classes that tailor your layout based on screen size. To "flex" on larger devices, you typically utilize the flex and justify classes in combination with media breakpoints.
Use the flex-direction utilities to control how flex items are arranged within the container.
<div class="flex justify-between sm:justify-center lg:justify-around">
<div class="bg-red-500 w-24 h-24"></div>
<div class="bg-blue-500 w-24 h-24"></div>
<div class="bg-green-500 w-24 h-24"></div>
</div>